#Iftikhar j. kullo trial

Models, older age, female sex, greater body mass index, lower ABI, and a measure ofĪrterial stiffness (higher AIx and PP, lower T r) were associated with a lower walking distance. Iftikhar J Kullo M D Doctors and Medical Staff Mayo Clinic Paying forward the gift of life Mayo Clinic Bronchoscopy Care at Mayo Clinic Mayo Clinic. In both multivariable accelerated failure time (AFT) and Cox proportional-hazards He received his medical degree from Government Medical. heart disease) or stroke, and CAC score was calculated using the method described by Agatston and co-workers (1990) J. To account for right-censoring of walking distances in patients completing theĥ min walk ( n = 56), we used survival analysis to identify variables associated with walking distance. Kullo is a cardiologist in Rochester, Minnesota and is affiliated with Mayo Clinic. Were measured as per laboratory protocol after excluding patients with non-compressible Division of Cardiovascular Diseases, Mayo Clinic and Foundation. Ankle-brachial index (ABI) and walking distance (AIx) is the difference between the first and second systolic peak of the ascendingĪortic pressure waveform indexed to the pulse pressure (PP) and T r is the reflected wave arrival time. About Press Copyright Contact us Creators Advertise Developers Terms Privacy Policy & Safety How YouTube works Test new features NFL Sunday Ticket Press Copyright. Radial artery pulse waveforms were obtained by applanation tonometry and an ascendingĪortic pressure waveform derived by a transfer function. Patients ( n = 106, 69 ± 10 years, 66% men) referred for lower extremity arterial evaluation were studied. Ethics declarations Competing interests The authors declare no competing interests. Iftikhar Kullo is a Professor of Medicine at Mayo Clinic Rochester, MN. Kullo has authored 248 scientific papers, and he is the co-Principal Investigator of the Mayo electronic Medical Records and GEnomics (eMERGE) grant.We hypothesized that measures of arterial stiffness and wave reflection influenceįunctional capacity of patients with peripheral arterial disease (PAD). Kullo Corresponding author Correspondence to Maya S. He directs the Early Atherosclerosis and Familial Hypercholesterolemia Clinics at Mayo Clinic Rochester, these evaluate and treat patients with premature vascular disease and genetic dyslipidemias.ĭr.

#Iftikhar j. kullo trial

Kullo led the MI-GENES study - the first genomic medicine clinical trial to demonstrate that incorporating genetic risk information can alter a health outcome. His research program is funded by the NIH since 2003 and includes both genomic medicine discovery and implementation projects.Kullo's research is focused on the genetics of atherosclerosis and lipid disorders. He completed residency training in Internal Medicine, including the Clinician Investigator training pathway and subsequently a Fellowship in Cardiovascular Diseases at Mayo Clinic. Iftikhar Kullo is a Professor of Medicine at Mayo Clinic Rochester, MN.